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No fetotoxicity was noticed right after oral metronida-zole in rats or mice. Having said that, because animal replica research are usually not constantly predictive of human response and given that oral metron-idazole continues to be revealed being a carcinogen in some rodents, this drug need to be utilised in the course of pregnancy provided that clearly wanted.
Oral metronidazole is reported to potentiate the anticoagulant outcome of warfarin and other coumarin anticoagulants, leading to a prolongation of prothrombin time.